General Clinical Chemistry Analyzers and Accessories
Abcam Dabrafenib, mutant B-Raf V600E inhibitor, 25MG
MW 519.6 Da, Purity >98%. Potent, ATP-competitive mutant B-Raf V600E inhibitor (IC50 = 0.7 nM), with selectivity versus wild-type B-Raf (IC50 = 5.2 nM) and c-RAf (IC50 = 6.3 nM) in cell-free assays. Antitumor activity *in vivo* in mouse models of B-Raf V600E melanoma.
The product is subject to the following: Abcam Restricted Use Statement
Roche Diagnostics Glutamate V2 Bio HT Test kit for Cedex BioHT Analyzer
Glutamate V2 Bio HT Test kit for the Cedex Bio HT Analyzer
Abcam FC 131, C x CR4 activation inhibitor, 10MG
MW 729.8 Da, Purity >95%. FC 131, CXCR4 activation inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Anton Paar For dry measurements using compressed air.Suitable for particles of up to 3500 µm (default).Pressure: 0.05-4.6 bar
DRY JET DISPERSION UNITFor dry measurements using compressed air.Suitable for particles of up to 3500 µm (default).Pressure: 0.05-4.6 bar.Sample funnel volume: 150 mL (default). Optional: 600 mL.Superior protection against sample spread.Automated feeding rate.Requires vacuum cleaner for operation.Minimum requirements to run:- Supply of compressed gas 5 - 10 bar- Compatible vacuum cleaner- 257436 Air dryer IDG 30 with air filter unit
Hach Company CLT10sc Total CL Analyzer w/pH
CLT10sc Total Chlorine Analyzer (Panel Only) with Combination pH SensorIncludes CL10 sc Panel-1 m digital extension cable-Panel Manual-Combination pH Sensor Manual-Chlorine Sensor Manual
Abcam Elevenostat, 1MG
MW 315.32 g/mol, Purity >=95%. A small molecule hydroxamic acid derivative that acts as a HDAC11-selective inhibitor. Reporter assays using a luciferase-linked Foxp3 promoter shows that HDAC11 decreases the signal driven by NFκB/p65, alone or in the presence of transfected Foxp3, and impairs luciferase activity driven by p65, Foxp3 and the HAT enzyme, p300. The inhibitory effects of HDAC11 at the Foxp3 promoter are reversed by Elevenostat (JB3-22), (IC₅₀ 0.235 μM). Elevenostat also partially reverses the inhibitory effect of HDAC11 on p300-induced Foxp3 acetylation at lysine 31 consistent with the ability of HDAC11 to directly regulate acetylation of Foxp3.
The product is subject to the following: Abcam Restricted Use Statement
Roche Diagnostics OD Bio HT, 400 tests
The most common method to monitor the growth in bacterial and yeast cultures is the determination of the optical density of the culture suspension, which relates to the number of cells per culture volume. The manual procedure to prepare the required diutions and to perform the measurements on a photometer is usually very imprecise, error-prone and laborious. The automated testing using a Cedex Bio or Cedex Bio HT Analyzer, offers a standardized OD determination with high precison, reliability and convenience.
Abcam YM-155, survivin inhibitor, 5MG
MW 443.3 Da, Purity >98%. Novel small molecule potent survivin suppressant. Inhibits survivin promoter activity (IC₅₀ = 0.54 nM) and down-regulates survivin in vitro and in vivo. Induces apoptosis in human tumor cell lines in vitro at 10 nM, with little effect on other IAP or Bcl-2 family members.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB-525334, TGFBR1 inhibitor., 25MG
MW 343.4 Da, Purity >98%. Cell permeable, potent, selective transforming growth factor beta 1 receptor (ALK5) (IC₅₀ = 14.3 nM) and ALK4 (IC₅₀ = 58.5 nM) inhibitor, with no activity at ALK2, 3 and 6 (IC₅₀ > 10 μM). Blocks fibrosis and renal injury markers in a puromycin-induced nephritis model. Causes significant attenuation in Smad2/3 nuclear translocation and a decrease in CTGF-expressing cells, myofibroblast proliferation and type 1 collagen deposition resulting in an overall attenuation in bleomycin-induced pulmonary fibrosis.
The product is subject to the following: Abcam Restricted Use Statement