General Clinical Chemistry Analyzers and Accessories
Abcam LCL161, 5MG
MW 500.6 Da, Purity >99%. Small molecule SMAC mimetic inhibitor of multiple IAP (Inhibitor of apoptosis) family proteins. (IC₅₀ = 10.23 μM). Inhibits cell proliferation and viability in two human hepatocellular carcinoma cells (Hep3B, IC₅₀ = 10, and PLC5, IC₅₀ = 19).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Umifenovir, 5MG
MW 477.4 Da, Purity >=95%. An indole derivative with broad-spectrum antiviral activity. It inhibits virus-mediated fusion with target membrane and blocks virus entry into target cells. It shows antiviral activity against many enveloped or non-enveloped RNA or DNA viruses with IC₅₀ values ranging from 0.41 to 16 uM. It (50 or 100 mg/kg/day) reduces mean pulmonary virus yields and the rate of mortality in mice infected with FLU-A (A/PR/8/34 H1N1). Molecular dynamics and structural analysis show that Umifenovir may target SARS-CoV-2 spike glycoprotein and may block its trimerization which will reduce cell adherence and virus entry.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Indo x imod, Indoleamine 2,3-dio x ygenase (IDO) inhibitor, 1G
MW 218.25 Da, Purity >95%. Methylated tryptophan which acts as an Indoleamine 2,3-dioxygenase (IDO) inhibitor. Prevents T-cell anergy triggered by dendritic cells overexpressing IDO in mice.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen 3-oxo-C6-DL-HSL
Chemical. CAS 76924-95-3. Formula C10H15NO4. MW 213.2. Synthetic. N-3-Oxohexanoyl-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. At increased populations of bacteria, localized higher concentrations of 3OC6-HSL, an endogenous ligand to transcriptional factor LuxR, leads to increased production of both the AHL synthase and proteins responsible for bioluminescence. Numerous other species of bacteria also employ 3OC6-HSL in cell-to-cell communication. An autoinducer of P. fischeri luciferase and a specfic genetic regulator that is unrelated to at least one of the enzyme systems that it induces.
AdipoGen Tetrakistrimethylsilylsilane
Chemical. CAS 4098-98-0. Formula CH33Si4Si. MW BD9837. Tetrakistrimethylsilylsilane TTMSS is an organosilicon compound. TTMSS is widely used as a reagent and precursor in organic synthesis and silicon-based chemistry. TTMSS is commonly used as a protecting group for various functional groups in organic synthesis, in deoxygenation reactions to remove oxygen-containing functional groups like ketones, aldehydes, and esters, converting them into the corresponding trimethylsilyl ethers. TTMSS is utilized in silylation reactions to introduce trimethylsilyl groups onto organic compounds, enhancing their volatility and stability for gas chromatography and mass spectrometry analysis. Due to its diverse applications in organic chemistry, Tetrakistrimethylsilylsilane has become a valuable tool for synthetic chemists, particularly in the fields of silicon-based chemistry, protecting group strategies, and cross-coupling reactions.
Abcam STING Inhibitor, C-176, 25MG
MW 358.09 Da, Purity >=98%. STING inhibitor C-176 is a potent, small-molecule inhibitor of STING (stimulator of interferon genes) protein, that attenuates STING-associated autoinflammatory disease in mice. STING protein is a central signaling component of the intracellular DNA sensing pathway.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Cordycepin
Chemical. CAS 73-03-0. Formula C10H13N5O3. MW 251.24. Synthetic. Cordycepin is a nucleoside adenosine analog antibiotic that acts as a polyadenylation inhibitor when converted to 3’-deoxyadenosine triphosphate 3-dATP, which inhibits ATP-dependent DNA and RNA synthesis. Cordycepin has a broad spectrum of biological activities, including anticancer, anti-proliferative, pro-apoptotic, anti-inflammatory and antifungal effects. It was shown to modulate autophagy and NLRP3 inflammasome. Cordycepin has been shown to reduce polyA tail length in mRNA, to activate AMPK kinase, leading to a reduction in mTOR signalling, downregulate ERK/Akt/PI3K/GSK-3beta/beta-catenin signaling pathways. Also useful for the study of messenger RNA transcription.
Carterra CMDP CHIP MIN QTY 5
Please order in quantity of 5 or greater for this price
Bellco Glass, Inc. Anti-Foam Assembly , 15L
Adjustable anti-foam probe works by conductance. Rising level in bioreactor contacts the probe to trigger the controller for addition of anti-foam or addition / withdraw of media to maintain proper liquid level. Fits into 18 mm port on 3L metric head plate. Supplied with nut, washers and O-Rings. MADE IN THE USA
Bellco Glass, Inc. Stainless Steel Shaft Assembly , 6-8L
Stainless Steel Shaft Assembly The Bellco Stainless Steel Shaft Conversion Kit is designed to convert your standard glass shaft to stainless steel on 1967 and1965 Spinner Flasks. Sizes range from 100 mL to 36 liters for 1965 spinners and 100 to 3000 mL for 1967 spinner flasks. Material: 316L Stainless. MADE IN THE USASteel and polypropylene compression fitting. Size: 6-8l
Enterprise Technology Solutions Vileda Professional Mop Pad,Microfiber,Color-Coded Tags,14"L
UltraSpeed Mini MicroLite General-Purpose Mop Pad is made of microfiber for effective cleaning. 14" long pad is small in size but big on performance. Color-code your cleaning process with the cutoff tags to meet hygiene standards. Reusable design is machine-washable. It is compatible with UltraSpeed Mini System (not included) for a complete cleaning system.